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Title: Pivagabine  
Author: World Heritage Encyclopedia
Language: English
Subject: Citrulline, ATC code N06, N-Acetylglutamic acid, Acetyllysine
Publisher: World Heritage Encyclopedia



CAS number 69542-93-4 YesY
PubChem 68888 YesY
ChemSpider 62118 YesY
EC number 274-038-3
KEGG D07342 YesY
MeSH N-trimethylacetyl-4-aminobutyric+acid
ATC code AX15
Jmol-3D images Image 2
Molecular formula C9H17NO3
Molar mass 187.24 g mol−1
Routes of
6.4 hours
Legal status

Prescription only

Related compounds
Related alkanoic acids
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Pivagabine (Tonerg) is an antidepressant and anxiolytic drug which was introduced in Italy in 1997 for the treatment of depressive and maladaptive syndromes. But it was discontinued in Italy (according to Martindale). Originally believed to function as a prodrug to GABA,[1] pivagabine is now believed to act via its inhibitory effects on corticotropin-releasing factor (CRF).[2][3][4][5]

See also


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