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Title: Cloroqualone  
Author: World Heritage Encyclopedia
Language: English
Subject: Mebroqualone, Etaqualone, Mecloqualone, Diproqualone, Alcoholic beverage
Collection: Chloroarenes, Gabaa Receptor Positive Allosteric Modulators, Organochlorides, Quinazolinones, Sedatives
Publisher: World Heritage Encyclopedia


Systematic (IUPAC) name
Clinical data
  • ?
Routes of
Pharmacokinetic data
Bioavailability ?
Metabolism ?
Biological half-life ?
Excretion ?
CAS Registry Number  N
ATC code None
PubChem CID:
DrugBank  N
ChemSpider  YesY
Chemical data
Formula C16H12Cl2N2O
Molecular mass 319.185

Cloroqualone is a quinazolinone-class GABAergic and is an analogue of methaqualone developed in the 1980s and marketed mainly in France and some other European countries. It has sedative and antitussive properties resulting from its agonist activity at the β subtype of the GABAa receptor and sigma-1 receptor, and was sold either alone or in combination with other ingredients as a cough medicine. Cloroqualone has weaker sedative properties than methaqualone and was sold for its useful cough-suppressing effects, but was withdrawn from the French market in 1994 because of concerns about its potential for abuse and overdose.

See also


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