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Cortivazol

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Title: Cortivazol  
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Cortivazol

Cortivazol
Systematic (IUPAC) name
(11β,16α)-21-(Acetyloxy)-11,17-dihydroxy-6,16-dimethyl-2'-phenyl-2'H-pregna-2,4,6-trieno[3,2-c]pyrazol-20-one
Clinical data
AHFS/Drugs.com
Identifiers
CAS Registry Number  Y
ATC code H02
PubChem CID:
ChemSpider  Y
UNII  Y
KEGG  Y
ChEMBL  N
Chemical data
Formula C32H38N2O5
Molecular mass 530.655
 N   

Cortivazol is a high-affinity agonist ligand for the glucocorticoid receptor and consequently is classified as a glucocorticoid.[1]

It is sometimes abbreviated "CVZ".[2]

References

  1. ^ Schlechte JA, Simons SS, Lewis DA, Thompson EB (October 1985). "[3H]cortivazol: a unique high affinity ligand for the glucocorticoid receptor". Endocrinology 117 (4): 1355–62.  
  2. ^ Yoshikawa N, Yamamoto K, Shimizu N, Yamada S, Morimoto C, Tanaka H (May 2005). "The distinct agonistic properties of the phenylpyrazolosteroid cortivazol reveal interdomain communication within the glucocorticoid receptor". Mol. Endocrinol. 19 (5): 1110–24.  

External links

Cortivazol at the US National Library of Medicine Medical Subject Headings (MeSH)



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