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Title: Emylcamate  
Author: World Heritage Encyclopedia
Language: English
Subject: Alcoholic beverage, Spirobarbital, Centalun, Nitromethaqualone, Pentabamate
Collection: Anxiolytics, Carbamates, Gabaa Receptor Positive Allosteric Modulators, Muscle Relaxants
Publisher: World Heritage Encyclopedia


Systematic (IUPAC) name
3-methyl-3-pentanol carbamate
CAS Registry Number  Y
ATC code N05
PubChem CID:
ChemSpider  Y
Chemical data
Formula C7H15NO2
Molecular mass 145.20 g·mol−1

Emylcamate (marketed as Striatran by Merck) is an anxiolytic and muscle relaxant. It was patented in the US in 1961 (US Patent 2,972,564) and advertised for the treatment of anxiety and tension. It was claimed to be superior to meprobamate, which was the market leader at the time. It is no longer prescribed.

A study of the drug's effects in mice was done in 1959. It concluded that at 50 mg/kg emylcamate gave a 63% decrease in motor activity compared to meprobamate's 32% decrease, a doubling in effective potency. The therapeutic index in mice was also established:

Meprobamate Emylcamate Effect
175 123 ED50 (mg/kg)
600 550 LD50 (mg/kg)
3.4 4.4 Therapeutic index

Emylcamate also has a faster intra-parenteral onset then meprobabamate, 3 minutes compared to 35. [1]


  1. ^ Melander, B. (1959). "Emylcamate, A Potent Tranquillizing Relaxant". Journal of Medicinal and Pharmaceutical Chemistry 1 (5): 443–457.  
  • Olhando para trás: um novo caminho possível para a descoberta de drogas em psicofarmacologia (Portuguese)
  • The Comparative Toxicogenomics Database: Emylcamate.
  • BIAM: Emylcamate (French).

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