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Etynodiol

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Etynodiol

Etynodiol
Systematic (IUPAC) name
(3β,17β)-17-ethynylestr-4-ene-3,17-diol
Identifiers
CAS Registry Number
ATC code G03
PubChem CID:
ChemSpider
Chemical data
Formula C20H28O2
Molecular mass 300.435 g/mol

Etynodiol (INN), or ethynodiol (BAN), is a steroidal progestin which was never marketed.[1][2] A diacylated derivative, etynodiol diacetate, is used as a hormonal contraceptive.[1][2]

While etynodiol is sometimes used as a synonym for etynodiol diacetate, what is usually being referred to is actually etynodiol diacetate and not etynodiol.

Synthesis

Ethynodiol diacetate synthesis:[3] F. B. Colton, U.S. Patent 2,843,609 (1958 to Searle). Prepn of the 3-acetate, 17-acetate, and diacetate: P. D. Klimstra, U.S. Patent 3,176,013 (1965 to Searle); see also:[4]

See also

References

  1. ^ a b F.. Macdonald (1997). Dictionary of Pharmacological Agents. CRC Press. p. 1454.  
  2. ^ a b Index Nominum 2000: International Drug Directory. Taylor & Francis US. 2000. p. 422.  
  3. ^ Klimstra, P.; Colton, F. (1967). "The synthesis of 3β-hydroxyestr-4-en-17-one and 3β-hydroxiandrost-4-en-17-one". Steroids 10 (4): 411.  
  4. ^ Sondheimer, F.; Klibansky, Y. (1959). "Synthesis of 3β-hydroxy analogues of steroidal hormones, a biologically active class of compounds". Tetrahedron 5: 15.  


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