Inner root sheath

The inner root sheath of the hair follicle is located between the outer root sheath and the hair shaft.[1] It is made of three layers: Henle's layer, Huxley's layer, and the cuticle.[2]

Henle's layer is the outermost layer of the inner root sheath, consisting of a single row of cubical transparent cells that do not contain nuclei. Huxley's layer is in the middle, made up of approximately two rows of flattened cells with granular protoplasm. The cuticle of the root sheath is in the center, continuous with the outermost layer of the hair fiber.[2]


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