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Jte 7-31

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Title: Jte 7-31  
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Subject: WIN 55,212-2, JWH-018, N-(S)-Fenchyl-1-(2-morpholinoethyl)-7-methoxyindole-3-carboxamide, UR-144, Cannabipiperidiethanone
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Jte 7-31

JTE 7-31
IUPAC name

2-[2-(4-hydroxyphenyl)ethyl]-5-methoxy-4-(pentylamino)-2,3-dihydro-1H-isoindol-1-one

Identifiers
CAS number  N
PubChem
ChemSpider  YesY
Jmol-3D images Image 1
Properties
Molecular formula C22H28N2O3
Molar mass 368.469
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N   YesY/N?)

JTE 7-31 is a selective cannabinoid receptor agonist invented by Japan Tobacco.[1][2] It is a reasonably highly selective CB2 agonist, but still retains appreciable affinity at CB1, with a Ki of 0.088nM at CB2 vs 11nM at CB1.

See also

References

  1. ^ WO patent 1997/029079, Inaba T, Kaya T, Iwamura H, "Novel compounds and pharmaceutical use thereof", granted 1997-14-08 
  2. ^ US patent 6017919, Inaba T, Kaya T, Iwamura H, "Compounds and pharmaceutical use thereof", granted 2000-01-25 
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