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Title: Kcnj12  
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Subject: Cardiac action potential, Inward-rectifier potassium ion channel
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Potassium inwardly-rectifying channel, subfamily J, member 12
PDB rendering based on 3JYC.
Available structures
PDB Ortholog search: RCSB
KCNJ12 Gene
RNA expression pattern

ATP-sensitive inward rectifier potassium channel 12 is a protein that in humans is encoded by the KCNJ12 gene.[1][2][3][4]


This gene encodes an inwardly rectifying K+ channel that may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels that contribute to the cardiac inward rectifier current (IK1). The gene is located within the Smith-Magenis syndrome region on chromosome 17.[4]


KCNJ12 has been shown to interact with LIN7C,[5][6] DLG4,[5][6] LIN7B,[5][6] DLG2,[5] DLG3,[5] DLG1,[5][6][7] APBA1,[5][6] LIN7A[5][6] and CASK.[5][6]

See also


Further reading

External links

  • Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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