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Lesopitron (E-4424) is a selective full agonist of the 5-HT1A receptor which is structurally related to the azapirones.[1] In 2001 it was under development by Esteve as an anxiolytic for the treatment of generalized anxiety disorder (GAD).[2][3] It made it to phase II clinical trials but was apparently discontinued as no new information on lesopitron has surfaced since.[2][3]
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Sociology, Social psychology, Memory, Experimental psychology, Psychology
5-Methoxytryptamine, Metitepine, Lysergic acid diethylamide, Bromocriptine, Methysergide
5-Carboxamidotryptamine, Metitepine, Lysergic acid diethylamide, Bromocriptine, Methysergide
Medicine, Schizophrenia, Psychology, Psychotherapy, Neuroimaging
Psychology, 5-Carboxamidotryptamine, 5-Methoxytryptamine, Metitepine, Psychiatry
5-Carboxamidotryptamine, 5-Methoxytryptamine, Lysergic acid diethylamide, Metitepine, Methysergide
Ergoline, Serotonin, Lysergic acid diethylamide, 5-Methoxytryptamine, Substituted tryptamine
5-Carboxamidotryptamine, 5-Methoxytryptamine, Metitepine, Lysergic acid diethylamide, Bromocriptine
Serotonin, Ergoline, Lysergic acid diethylamide, 5-Methoxytryptamine, Substituted tryptamine