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Milacemide

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Title: Milacemide  
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Subject: Safinamide, Methoxetamine, Indantadol, Serine, List of dopaminergic drugs
Collection: Amino Acid Derivatives, Glycine Receptor Agonists, Monoamine Oxidase Inhibitors
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Milacemide

Milacemide
Skeletal formula of milacemide
Identifiers
CAS number  YesY
PubChem
ChemSpider  YesY
UNII  YesY
MeSH
ChEMBL  YesY
Jmol-3D images Image 1
Image 2
Properties
Molecular formula C7H16N2O
Molar mass 144.21 g mol−1
log P 0.754
Related compounds
Related compounds Tricine
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)

Milacemide is an MAO-B inhibitor and glycine prodrug.[2] It has been studied for its effects on human memory and as a potential treatment for the symptoms of Alzheimer's disease.[3] Early clinical trials did not show positive results however,[2] and the drug is now abandoned.

References

  1. ^ "milacemide - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 8 August 2005. Identifiers and Related Records. Retrieved 9 January 2012. 
  2. ^ a b Dysken, MW; Mendels, J; LeWitt, P; Reisberg, B; Pomara, N; Wood, J; Skare, S; Fakouhi, JD; Herting, RL (May 1992). "Milacemide: a placebo-controlled study in senile dementia of the Alzheimer type.". Journal of the American Geriatrics Society 40 (5): 503–6.  
  3. ^ Harris, Carol Turkington ; foreword by Joseph R. (2002). The encyclopedia of the brain and brain disorders (2nd ed. ed.). New York, NY: Facts on File.  



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