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Mitragynine pseudoindoxyl

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Title: Mitragynine pseudoindoxyl  
Author: World Heritage Encyclopedia
Language: English
Subject: Mitragyna speciosa, Δ-opioid receptor, List of opioids, Kobret, 6β-Naltrexol-d4
Collection: Delta-Opioid Agonists, Ethers, Euphoriants, Indole Alkaloids, Indoloquinolizines, Mu-Opioid Agonists, Opiates
Publisher: World Heritage Encyclopedia

Mitragynine pseudoindoxyl

Mitragynine pseudoindoxyl
IUPAC name
Methyl (E)-2-((1′S,6′S,7′S,8a′S)-6'-ethyl-4-methoxy-3-oxo-3',5',6',7',8',8a'-hexahydro-2′H-spiro[indoline-2,1'-indolizin]-7'-yl)-3-methoxyacrylate
Other names
spiro[2H-indole-2,1'(5′H)-indolizine]-7'-acetic acid, 6'-ethyl-1,2',3,3',6',7',8',8'a-octahydro-4-methoxy-α-(methoxymethylene)-3-oxo-, methyl ester, (αE,2S,6′S,7′S,8′aS)
Jmol-3D images Image
Molar mass 414.50 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Mitragynine pseudoindoxyl is a semi-synthetic opioid compound derived from natural mitragynine found in the plant Mitragyna speciosa, commonly known as Kratom.[1]


Mitragynine pseudoindoxyl itself acts primarily via mu and delta opioid receptors, being more potent than morphine and about as potent as enkephalin.[2][3]

See also


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