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NBUMP is a highly selective 5-HT1A receptor partial agonist (Ki = 0.1 nM; IA = 40%) with an arylpiperazine structure.[1] It is one of the highest affinity ligands for the 5-HT1A receptor known.[1] It displays 460- and 260-fold selectivity for 5-HT1A over the α1-adrenergic and D2 receptors, respectively.[1]
5-Methoxytryptamine, Metitepine, Lysergic acid diethylamide, Bromocriptine, Methysergide
5-Carboxamidotryptamine, Metitepine, Lysergic acid diethylamide, Bromocriptine, Methysergide
Amphetamine, Cocaine, Iron, Zinc, Methamphetamine
5-Carboxamidotryptamine, 5-Methoxytryptamine, Lysergic acid diethylamide, Metitepine, Methysergide
Ergoline, Serotonin, Lysergic acid diethylamide, 5-Methoxytryptamine, Substituted tryptamine
5-Carboxamidotryptamine, 5-Methoxytryptamine, Metitepine, Lysergic acid diethylamide, Bromocriptine
Serotonin, Ergoline, Lysergic acid diethylamide, 5-Methoxytryptamine, Substituted tryptamine