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Nafadotride

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Title: Nafadotride  
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Subject: List of dopaminergic drugs, Dopamine receptor D3, AS-8112, CY-208,243, Ro10-5824
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Nafadotride

Nafadotride
Identifiers
CAS number  YesY
PubChem
MeSH
ChEMBL  N
IUPHAR ligand
Jmol-3D images Image 1
Properties
Molecular formula C22H27N3O2
Molar mass 365.47 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N   YesY/N?)

Nafadotride is a dopamine antagonist with reasonable selectivity for the D3 subtype (9.6 times selectivity for D3 over D2).[1]


References

  1. ^ Pilla M, Perachon S, Sautel F, Garrido F, Mann A, Wermuth CG, Schwartz JC, Everitt BJ, Sokoloff P. Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 agonist. Nature. 1999;400:371–375.
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