World Library  
Flag as Inappropriate
Email this Article

Radial keratotomy

Article Id: WHEBN0000665554
Reproduction Date:

Title: Radial keratotomy  
Author: World Heritage Encyclopedia
Language: English
Subject: Eye surgery, Wikifun/Round 7/Answers/Question 4, List of -otomies, Iridectomy, Trabeculectomy
Collection: Eye Surgery, Russian Inventions, Soviet Inventions
Publisher: World Heritage Encyclopedia

Radial keratotomy

Radial keratotomy
Schematic diagram of RK, with incisions drawn in orange
ICD-9-CM 11

Radial keratotomy (RK) is a refractive surgical procedure to correct myopia (nearsightedness) that was developed in 1974, by Svyatoslav Fyodorov, a Russian ophthalmologist. Though it has been largely supplanted by newer operations, such as photorefractive keratectomy, LASIK, Epi-LASIK and the phakic intraocular lens, RK remains popular for correction of astigmatism in certain patients.


  • Development 1
  • Procedure 2
  • Results 3
  • Postsurgical healing 4
  • Complications 5
  • Visual rehabilitation after RK 6
  • References 7


Beginning in 1936, Japanese ophthalmologist Tsutomu Sato conducted research in anterior and posterior keratotomy, an early form of refractive surgery that attempted to treat keratoconus, myopia and astigmatism by making incisions in the cornea.[1]

In 1974, Svyatoslav Fyodorov removed glass from the eye of a boy who had been in an accident. The boy, who required eyeglasses for correction of myopia caused by astigmatism, fell off his bicycle. His glasses shattered on impact, and glass particles lodged in both eyes. To save the boy's vision, Fyodorov performed an operation which consisted of making numerous radial incisions extending from the pupil to the periphery of the cornea in a radial pattern like the spokes of a wheel. After the glass was removed by this method and the cornea healed, Fyodorov found that the boy's visual acuity had improved significantly.


In RK, incisions are made with a diamond knife. Incisions that penetrate only the superficial corneal stroma are less effective than those reaching deep into the cornea,[2] and consequently, incisions are made quite deep. One study cites incisions made to a depth equivalent to the thinnest of four corneal-thickness measurements made near the center of the cornea.[3] Other sources cite surgeries leaving 20 to 50 micrometres of corneal tissue unincised (roughly equivalent to 90% of corneal depth, based on thickness norms).[2]


Visual acuity is generally improved.[4]

Postsurgical healing

Cross-section schematic of postsurgical epithelial plugs. Example of a desirable outcome (left), and an undesirable outcome (right).

The healing corneal wounds consist of newly abutting corneal stroma, fibroblastic cells, and irregular fibrous connective tissue. Closer to the wound surface lies the epithelial plug, a bed of the cells that form the normal corneal epithelium which have fallen into the wound. Often this plug is three to four times as deep as the normal corneal epithelium layer. As the cells migrate from the depth of the plug up to the surface, some die before reaching it, forming breaches in the otherwise healthy epithelial layer. This, consequently, leaves the cornea more susceptible to infections.[5][6][7] The risk is estimated to be between 0.25%[8] and 0.7%[9] Healing of the RK incisions is very slow and unpredictable, often incomplete even years after surgery.[10] Similarly, infection of these chronic wounds can also occur years after surgery,[11][12][13] with 53% of ocular infections being late in onset.[14] The pathogen most commonly involved in such infections is the highly virulent bacterium Pseudomonas aeruginosa.[15]


Large epithelial plugs may cause more scattering of light, leading to the appearance of visual phenomena such as flares and starbursts — especially in situations such as night driving, where the stark light of car headlights abounds. These dark conditions cause the pupil to dilate, maximizing the amount of scattered light that enters the eye. In cases where large epithelial plugs lead to such aggravating symptoms, patients may seek further surgical treatment to alleviate the symptoms.[5]

Increasing altitude can cause partial blindness in people who have undergone RK, as discovered by mountaineer Beck Weathers (who had undergone RK) during the 1996 Mount Everest disaster.

The incisions of RK are used to relax the steep central cornea in patients with myopia. The original technique — consisting of incisions from periphery to center — was called "the Russian technique",[16] while the later advances of performing controlled incision from center to periphery was called "the American Technique".[17]

RK enjoyed great popularity during the 1980s, and was one of the most studied refractive surgical procedures. Its 10-year data was published as the PERK (Prospective Evaluation of Radial Keratotomy) study, which proved the onset of progressive hyperopia — often found a decade after the original surgery — is due to continued flattening of the central cornea.

A conceptually opposite technique of using hexagonal incisions in the periphery of the cornea is known has Hexagonal Keratotomy (HK, described by Antonio Mendez of Mexicali, Mexico), which was used to correct low degrees of Hyperopia. The idea behind HK was to make six peripheral incisions forming a hexagon around the central cornea to steepen the hyperopic flat cornea and, thereby, focus the rays of light more precisely onto the retina. These incisions can be of two types, either connecting or non-connecting.[18]

RK may be performed with different types, numbers, and patterns of incisions. They can have 4, 8, 12, 16 or 32 incisions made in a number of patterns and orientations based on refractive errors, surgeon style and surgeon training. Many of these patients have had additional incisional surgeries like Astigmatic Keratotomy (AK), where incisions are placed at the steepest points of the cornea in people with astigmatism to relax and transform the cornea to a more spherical shape. Some people have had a combination of intraocular surgeries, such as Pseudophakia or Phakic implants, along with their keratotomies and many underwent "purse-string" suturing to control over-correction (Dr. Green’s Lasso suture).

Due to the instability of the cornea seen with many age-related pathologies, it may be difficult to address visual acuity satisfactorily in people who have undergone RK surgery but who later develop presbyopia (hyperopia caused by age-related changes in the crystalline lens). In these situations, factors to be considered include:

Primary visual factors:

Decreased visual acuity (Myopia, Hyperopia, Astigmatism)
Irregular astigmatism
Small Optic Zone

Secondary (Associated) Visual Factors:

Corneal Scars
Corneal Instability (thin/ectasia/trampoline effect)

Visual rehabilitation after RK

The PERK study demonstrated that people who undergo RK continue to drift toward hyperopia ("farsightedness"). Additionally, many of these people have reached the age where presbyopia occurs. Some also develop cataracts. Their vision can still be restored with epilasik, photorefractive keratectomy, LASIK or phakic lens extraction, or cataract surgery. The corneal curvature has to re measured and modified by history, central keratometry, or contact lens method.


  1. ^ Sato, T (1939). "Treatment of conical cornea (incision of Descemet's membrane)". Acta Soc Ophthalmol Jpn (in Japanese) 43: 544–55. 
  2. ^ a b Bashour M, Benchimol M. (2005) Emedicine. Viewed 12 October 2006. Myopia, Radial Keratotomy
  3. ^ Waring GO, Moffitt SD, Gelender H, et al. (January 1983). "Rationale for and design of the National Eye Institute Prospective Evaluation of Radial Keratotomy (PERK) Study". Ophthalmology 90 (1): 40–58.  
  4. ^ Symons SP, Slomovic AR. Visual acuity, refractive and keratometric results of 140 consecutive radial keratotomy procedures. Canadian Journal of Ophthalmology. 1994 August; 29(4):176-181.
  5. ^ a b Bergmanson JP, Farmer EJ (1999). "A return to primitive practice? Radial keratotomy revisited". Cont Lens Anterior Eye 22 (1): 2–10.  
  6. ^ Bergmanson J, Farmer E, Goosey J (November 2001). "Epithelial plugs in radial keratotomy: the origin of incisional keratitis?". Cornea 20 (8): 866–72.  
  7. ^ Deg JK, Zavala EY, Binder PS (June 1985). "Delayed corneal wound healing following radial keratotomy". Ophthalmology 92 (6): 734–40.  
  8. ^ Waring GO, Lynn MJ, McDonnell PJ (October 1994). "Results of the prospective evaluation of radial keratotomy (PERK) study 10 years after surgery". Arch. Ophthalmol. 112 (10): 1298–308.  
  9. ^ Hoffer KJ, Darin JJ, Pettit TH, Hofbauer JD, Elander R, Levenson JE (June 1983). "Three years experience with radial keratotomy. The UCLA study". Ophthalmology 90 (6): 627–36.  
  10. ^ Binder PS, Nayak SK, Deg JK, Zavala EY, Sugar J (March 1987). "An ultrastructural and histochemical study of long-term wound healing after radial keratotomy". Am. J. Ophthalmol. 103 (3 Pt 2): 432–40.  
  11. ^ McClellan KA, Bernard PJ, Gregory-Roberts JC, Billson FA (May 1988). "Suppurative keratitis: a late complication of radial keratotomy". J Cataract Refract Surg 14 (3): 317–20.  
  12. ^ Mandelbaum S, Waring GO, Forster RK, Culbertson WW, Rowsey JJ, Espinal ME (August 1986). "Late development of ulcerative keratitis in radial keratotomy scars". Arch. Ophthalmol. 104 (8): 1156–60.  
  13. ^ Wilhelmus K, Hanburg S (June 1983). "Bacterial Keratitis following Radial Keratotomy". Cornea 2 (2): 143–6.  
  14. ^ Jain S, Azar DT (1996). "Eye infections after refractive keratotomy". J Refract Surg 12 (1): 148–55.  
  15. ^ Heidemann DG, Dunn SP, Chow CY (December 1999). "Early- versus late-onset infectious keratitis after radial and astigmatic keratotomy: clinical spectrum in a referral practice". J Cataract Refract Surg 25 (12): 1615–9.  
  16. ^ Gulani AC, Fyodorov S: Future Directions in Vision course, June 1997
  17. ^ Gulani AC, Neumann AC: Refractive Surgery Course, February 1996
  18. ^ Gulani AC: 10 Refractive Procedures for Hyperopia. ISOPT 2001
This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.

Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.