Sch-23,390

SCH 23390
Identifiers
CAS number 87075-17-0 YesY
PubChem 5018
ChEBI CHEBI:73297 YesY
IUPHAR ligand 943
Jmol-3D images Image 1
Properties
Molecular formula C17H18ClNO
Molar mass 287.78 g/mol
 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

SCH 23390 is a synthetic compound that acts as a D1 receptor antagonist and has either minimal or negligible effects on the D2 receptor.

In a 1990 study in rats SCH 23390 offered significant protection from death in dextroamphetamine overdosage, without providing protection from death by methamphetamine overdose. The compound provided significant protection from cocaine overdose in rats only at the lowest dose tested in the measurement series. This suggested that d-amphetamine and methamphetamine at high (lethal) doses have different mechanisms of toxicity in rats.[1]

References

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