SCH 23390
CAS number 87075-17-0 YesY
PubChem 5018
ChEBI CHEBI:73297 YesY
IUPHAR ligand 943
Jmol-3D images Image 1
Molecular formula C17H18ClNO
Molar mass 287.78 g/mol
 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

SCH 23390 is a synthetic compound that acts as a D1 receptor antagonist and has either minimal or negligible effects on the D2 receptor.

In a 1990 study in rats SCH 23390 offered significant protection from death in dextroamphetamine overdosage, without providing protection from death by methamphetamine overdose. The compound provided significant protection from cocaine overdose in rats only at the lowest dose tested in the measurement series. This suggested that d-amphetamine and methamphetamine at high (lethal) doses have different mechanisms of toxicity in rats.[1]


This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.