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Title: Sch-442,416  
Author: World Heritage Encyclopedia
Language: English
Subject: Adenosine receptor
Publisher: World Heritage Encyclopedia


CAS number 316173-57-6
PubChem 10668061
ChemSpider 8843413 YesY
Jmol-3D images Image 1
Molecular formula C20H19N7O2
Molar mass 389.410
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

SCH-442,416 is a highly selective adenosine A2a subtype receptor antagonist. It is widely used in its 11C radiolabelled form to map the distribution of A2a receptors in the brain, where they are mainly found in the striatum, nucleus accumbens, and olfactory tubercle.[1] Given its distribution in the brain, A2a receptors have been investigated for the treatment of various neurological disorders, and SCH-442,416 has shown promise in treatment of depression,[2] Parkinson's disease,[3] and catalepsy.[4]


External links

  • Molecular Imaging and Contrast Agent Database: SCH-442,416
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