Em Changes and Other Toxic Effects of Firemaster Bp-6 (Polybrominated Biphenyls) in the Mouse

By Corbett, T. H.

Book Id: WPLBN0000007029
Format Type: PDF eBook
File Size: 1.1 MB
Reproduction Date: 2005

Title:	Em Changes and Other Toxic Effects of Firemaster Bp-6 (Polybrominated Biphenyls) in the Mouse
Author:	Corbett, T. H.
Volume:
Language:	English
Subject:	Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections:	Government Library Collection, Disarmament Documents
Historic Publication Date:
Publisher:	United Nations- Office for Disarmament Affairs (Unoda)


Citation APA MLA Chicago Corbett, T. H. (n.d.). Em Changes and Other Toxic Effects of Firemaster Bp-6 (Polybrominated Biphenyls) in the Mouse. Retrieved from https://self.gutenberg.org/

Description
Government Reference Publication

Excerpt
Introduction: In 1975, we reported that the commercial mixture of FireMaster BP-6 was weakly teratogenic in mice, produced decreasing birth weights with increasing dosage during pregnancy in both mice and rats, and produced a marked increase in liver size and weight with a concomitant increase in P-450 activity (I). The dietary doses studied ranged from 50 to IOOO ppm. In the teratogenicity studies, rodents were fed FireMaster BP-6 in the diet from day 7 to day 18 of the pregnancy for mice and from day 7 to day 20 of the pregnancy for rats. The birth defects produced in mice included exencephaly and cleft palate. In the liver studies, the only dose tested was IOOO ppm in the diet for 11 days.