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World Health Organization : Year 1991, World Health Organization Rab.Res., No. 91.37: 2nd World Health Organization Consultation on Oral Immunization of Dogs Against Rabies

By World Health Organization

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Book Id: WPLBN0000008180
Format Type: PDF eBook:
File Size: 0.9 MB
Reproduction Date: 2005



Title: World Health Organization : Year 1991, World Health Organization Rab.Res., No. 91.37: 2nd World Health Organization Consultation on Oral Immunization of Dogs Against Rabies  
Author: World Health Organization
Volume:
Language: English
Subject: Health., Public health, Wellness programs
Collections: Medical Library Collection, World Health Collection
Historic
Publication Date:
Publisher: World Health Organization

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Health Organization, B. W. (n.d.). World Health Organization : Year 1991, World Health Organization Rab.Res., No. 91.37. Retrieved from https://self.gutenberg.org/


Description
Medical Reference Publication

Excerpt
1. INTRODUCTION The first WHO Consultation on Oral Immunization of Dogs was held in Geneva from 26-27 February 1988 (report - WHO/Rab.Res./88.26). On the basis of tne recommendations of the first consultation together with those of the WHO Consultation on Requirements and Criteria for Field Trials on Oral Rabies Vaccination of Dogs and Wild Carnivores, Geneva, 1-2 March 1989 (report WHO/Rab .Res . /89.32), a number of candidate vaccine strains, baits and bait delivery systems were tested under laboratory (vaccines) and field (baits and bait delivery) conditions.

Table of Contents
TABLE OF CONTENTS Panes 1. INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2. REVIEW OF RESEARCH CONDUCTED ON ORAL IMMUNIZATION . . . . . . . . . . 3 2.1 Candidatevaccines . . . . . . . . . . . . . . . . . . . . . . . 3 2.1.1 Vaccinia-rabies recombinant (VRG), SAG1, and ERA strains . 3 2.1.2 SAD-BernandSAGl . . . . . . . . . . . . . . . . . . . . 4 2.1.3 Human Adenovirus 5 rabies recombinant in carni-vores . . . 5 2.1.4 Inactivated vaccines for oral immunization . . . . . . . . 5 2.2 Baits and bait delivery systems . . . . . . . . . . . . . . . . . 5 2.2.1 Testing of four bait types in Tunisia . . . . . . . . . . 5 2.2.2 Dog bait preference field tests in Mexico . . . . . . . . 6 2.3 Comuarison of parenteral versus oral vaccination strategies . . . 8 2.3.1 InruralMexico . . . . . . . . . . . . . . . . . . . . . 8 2.3.2 In Tunisia . . . . . . . . . . . . . . . . . . . . . . . . 9 2.4 Other studies related to oral immunization of dons' . . . . . . . 9 2.4.1 Estimating dog population size in an urban area . . . . . 9 2.4.2 Parenteral vaccination campaign in Nepal . . . . . . . . . 11 2.4.3 General considerations on feasibility of oral vaccination projects.. . . . . . . . . . . . . . . . . . . . . . . 11 3 . GUIDELINES FOR FURTHER RESEARCH INTO ORAL IMMUNIZATION OF DOGS . . . . 12 3.1 Determinine oral vaccine efficacy in the laboratorv . . . . . . . 12 3.1.1 Administration of vaccine . . . . . . . . . . . . . . . . 12 3.1.2 Vaccinetitration . . . . . . . . . . . . . . . . . . . . 13 3.1.3 Dog characteristics . . . . . . . . . . . . . . . . . . . 13 3.1.4 Immune response . . . . . . . . . . . . . . . . . . . . . 13 3.1.5 Viruschallenge . . . . . . . . . . . . . . . . . . . . . 13 3.1.6 Vaccination of dogs by baits . . . . . . . . . . . . . . . 14

 
 



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