Concentrations of Organochlorines Related to Titers to Epstein-Barr Virus Early Antigen Igg as Risk Factors for Hairy Cell Leukemia

By Hardell, Lennart

Book Id: WPLBN0000068549
Format Type: PDF eBook
File Size: 0.2 MB
Reproduction Date: 2005

Title:	Concentrations of Organochlorines Related to Titers to Epstein-Barr Virus Early Antigen Igg as Risk Factors for Hairy Cell Leukemia
Author:	Hardell, Lennart
Volume:
Language:	English
Subject:	Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections:	Government Library Collection, Disarmament Documents
Historic Publication Date:
Publisher:	United Nations- Office for Disarmament Affairs (Unoda)


Citation APA MLA Chicago Hardell, L. (n.d.). Concentrations of Organochlorines Related to Titers to Epstein-Barr Virus Early Antigen Igg as Risk Factors for Hairy Cell Leukemia. Retrieved from http://self.gutenberg.org/

Description
Government Reference Publication

Excerpt
Excerpt: Non-Hodgkin lymphoma (NHL) is a heterogeneous group of malignancies originating from the lymphoid system. There has been a rapid increase in NHL incidence in the Western world during the last 20?30 years (1?3). Hairy cell leukemia (HCL) is, according to modern classifications, a rare type of malignant lymphoma that expresses a B-cell phenotype (4). HCL is 4?5 times more frequent in males. The possible effects on environmental factors in the pathogenesis of HCL have been investigated (5?11), although the impact of genetic factors has not been evaluated. Many conditions characterized by severe immunosuppression, such as immunosuppressive treatment after organ transplantation, certain inborn immunodeficiencies, and human immunodeficiency virus (HIV) infection are correlated to an increased risk for NHL (12?14). Some factors suggested as possible risk factors for NHL, such as exposure to ultraviolet light and organochlorines, have been reported to induce immunologic changes (15,16), although the clinical importance of these findings has not been fully evaluated (17).