Adducted Proteins for Identification of Endogenous Electrophiles

By Kautiainen, Antti

Book Id: WPLBN0000100466
Format Type: PDF eBook
File Size: 0.5 MB
Reproduction Date: 2005

Title:	Adducted Proteins for Identification of Endogenous Electrophiles
Author:	Kautiainen, Antti
Volume:
Language:	English
Subject:	Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections:	Government Library Collection, Disarmament Documents
Historic Publication Date:
Publisher:	United Nations- Office for Disarmament Affairs (Unoda)


Citation APA MLA Chicago Kautiainen, A. (n.d.). Adducted Proteins for Identification of Endogenous Electrophiles. Retrieved from http://self.gutenberg.org/

Description
Government Reference Publication

Excerpt
Introduction: In vivo dose monitoring by means of adducts to macromolecules and characterization of electrophilic reagents of endogenous origin in humans not knowingly exposed to carcinogens is of interest for several reasons. Primarily, these studies are an important step in assessing the total load of mutagens and carcinogens in human populations and in developing preventive measures when the associated risks are high. Furthermore, studies of these kinds are required for the optimizsion of dose monitoring of low molecula weight exogenous carcinogens because background of adducts identical with the ones to be measured have been encountered in manv cases (,1 -3.).