Making the Libraries Sorting the Chromosomes

Book Id: WPLBN0000107342
Format Type: PDF eBook:
File Size: 0.1 MB
Reproduction Date: 2008

Title:	Making the Libraries Sorting the Chromosomes
Author:
Volume:
Language:	English
Subject:	Government publications, Legislation., Government Printing Office (U.S.)
Collections:	Government Library Collection
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Publisher:	Government Printing Office


Citation APA MLA Chicago Making the Libraries Sorting the Chromosomes. (n.d.). Making the Libraries Sorting the Chromosomes. Retrieved from https://self.gutenberg.org/

Excerpt
Excerpt: Before the advent of flow cytometry, human metaphase chromosomes could be coarsely partitioned into at most ten fractions by centrifugation or sedimentation techniques. Now. a state-of- the-art flow cytometer can separate these chromosomes. with an accuracy of up 95 percent and at a rate of up to 400 per second. into twenty-four fractions, one for each of the two sex chromosomes and the twenty-two homologous pairs of autosomes. Originally developed at Los Alamos in the late 1960s to measure the DNA content of cells, the flow cytometer is absolutely essential to our goal of producing very pure and highly representative chromosome-specific libraries of DNA fragments.

Table of Contents
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