World Health Organization : Technical Report Series, No. 472 - in Spanish: Methods of Fertility Regulation ; Advances in Research and Clinical Experience

By J. C. Cobb

Book Id: WPLBN0000131722
Format Type: PDF eBook
File Size: 2.1 MB
Reproduction Date: 2005

Title:	World Health Organization : Technical Report Series, No. 472 - in Spanish: Methods of Fertility Regulation ; Advances in Research and Clinical Experience
Author:	J. C. Cobb
Volume:
Language:	English
Subject:	Health., Public health, Wellness programs
Collections:	Medical Library Collection, World Health Collection
Historic Publication Date:
Publisher:	World Health Organization


Citation APA MLA Chicago Cobb, J. C. (n.d.). World Health Organization : Technical Report Series, No. 472 - in Spanish. Retrieved from http://self.gutenberg.org/

Description
Medical Reference Publication

Excerpt
INTRODUCTION The World Health Organization has convened several scientific groups on methods of fertility control. During the past few years, meetings have been devoted to such topics as intrauterine devices,l periodic abstinence,Z hormonal contraceptives,3 developments in fertility contro1,e immunological approaches,5 and the problem of abortion.6 Other meetings, such as the one on the health aspects of family planning,7 have also touched on questions of contraception. The purpose of the present meeting was to review certain developments in approaches to fertility control that have taken place during the past 3 years, with special emphasis on advances in knowledge of mechanisms of action of different methods, clinical experience on effectiveness and side effects, and research strategies for the development of improved methods. Attention was focused on the assessment of the methods used in evaluating the problems of contraceptive effectiveness and side effects. The Group was aided in its work by the reports of several previous WHO scientific groups,lj3,4>s and the present report will concentrate on developments that have occurred since the publication of these reports.

Table of Contents
CONTENTS Page 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 2 . Mechanisms of action of hormonal contraceptive steroids and intrauterine devices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 2.1 Mechanism of action of hormonal contraceptives . . . . . . . . . . 6 2.2 Mechanism of action of intrauterine devices . . . . . . . . . . . . 8 3 . Effectiveness and continuation of use of steroidal contraceptives and IUDs 12 3.1 Theoretical 'effectiveness . . . . . . . . . . . . . . . . . . . . . 13 3.2 Useeffectiveness and continuation of use . . . . . . . . . . . . . 15 4 . Side effects of steroidal contraceptives and IUDs . . . . . . . . . . . . 16 4.1 Methods of evaluating side effects of steroidal contraceptives . . . . 16 4.2 Metabolic effects of steroidal contraceptives . . . . . . . . . . . . 21 4.3 Clinical aspects of side effects of steroidal contraceptives . . . . . . 27 4.4 Side effects of IUDs . . . . . . . . . . . . . . . . . . . . . . 33 5. Indications and contraindications . . . . . . . . . . . . . . . . . . . 37 5.1 Oral contraceptives . . . . . . . . . . . . . . . . . . . . . . . 37 5.2 Intrauterine devices . . . . . . . . . . . . . . . . . . . . . . . 39 6 . Recent developments in clinical investigations . . . . . . . . . . . . . 40 6.1 Modifications of existing methods . . . . . . . . . . . . . . . . 40 7 . Research strategies and guidelines for the development of new methods of fertility control . . . . . . . . . . . . . . . . . . . . . . . . . . . . 44 7.1 Biology, sociology. and health service implications of reproduction . 45 7.2 Clinical trials and related toxicological investigations . . . . . . . . 45 7.3 Development of new products and techniques . . . . . . . . . . . 46 8. Research needs . . . . . . . . . . . . . . . . . . . . . . . . . . . 46