This article will be permanently flagged as inappropriate and made unaccessible to everyone. Are you certain this article is inappropriate? Excessive Violence Sexual Content Political / Social
Email Address:
Article Id: WHEBN0002102271 Reproduction Date:
InChI=1S/C66H83N17O13/c1-36(2)25-48(58(89)76-47(13-7-23-71-66(68)69)65(96)83-24-8-14-54(83)64(95)73-33-55(67)86)77-60(91)50(28-38-15-18-39-9-3-4-10-40(39)26-38)78-59(90)49(27-37-16-19-43(85)20-17-37)79-63(94)53(34-84)82-61(92)51(29-41-31-72-45-12-6-5-11-44(41)45)80-62(93)52(30-42-32-70-35-74-42)81-57(88)46-21-22-56(87)75-46/h3-6,9-12,15-20,26,31-32,35-36,46-54,72,84-85H,7-8,13-14,21-25,27-30,33-34H2,1-2H3,(H2,67,86)(H,70,74)(H,73,95)(H,75,87)(H,76,89)(H,77,91)(H,78,90)(H,79,94)(H,80,93)(H,81,88)(H,82,92)(H4,68,69,71)/t46-,47-,48-,49-,50+,51-,52-,53-,54-/m0/s1 Y Key:RWHUEXWOYVBUCI-ITQXDASVSA-N Y
Nafarelin is a gonadotropin-releasing hormone agonist (GnRH agonist). By causing constant stimulation of the pituitary gland, it decreases pituitary secretion of the gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH). Nafarelin may be used in the treatment of estrogen-dependent conditions (such as endometriosis or uterine fibroids), to treat central precocious puberty, or to control ovarian stimulation in IVF.
Nafarelin acetate is marketed by Searle (now part of Pfizer) under the brand name Synarel. It is delivered via a nasal spray.
Side effects of nafarelin are related to the low estrogen state. Side effects include hot flashes, vaginal dryness, headaches, mood changes, and decreased interest in sex. Some patients may experience acne, muscle pain, reduced breast size, and irritation of the tissue inside the nose. These side effects are reversible and should resolve after stopping the medication.[1]
Antagonists: Pegvisomant
: END
///
()//, /
, drug (////)
Diamond, Graphite, Solar system, Coal, /anolanthanide Chemistry
Oxygen, Argon, Hydrogen, Helium, Gold
Nitrogen, Hydrogen, Helium, Sulfur, Fluorine
GnRH Neuron, Follicle-stimulating hormone, Luteinizing hormone, Peptide, Hypothalamus
Follicle-stimulating hormone, In vitro fertilisation, Cancer, Prostate cancer, Buserelin
Carbon, Hydrogen, Chlorine, Nitrogen, Oxygen
ATC code H, ATC code A, Thyroid, Vasopressin, Salmon
Gonadotropin, Cancer, Gonadotropin-releasing hormone, Androgen, Estrogen
Carbon, Hydrogen, Fluorine, Nitrogen, Oxygen